Viagra online is primarily a vasodilator. This medicine can magnify the flow of blood to the pelvic region by dilating the vessels leading to it. When the blood vessels get expanded, the more blood passes through them and fills into the penis. The veins within the penis trap the blow until the climax. When the climax is reached the blood goes away from the penis.
The mechanism of Viagra action involves many important processes. The onset of erection is urged with sexual stimulation which helps to increase the amount of nitric oxide in the penile region. This substance is essential for the erection to occur. Sildenafil, the main component in Viagra selectively inhibits the enzyme PDE-5 which is located in the tissues of the penis. This enzyme affects the cGMP, the other important substance which regulates smooth muscle relaxation. If there is too much of PDE-5 in the penile tissue, a man experiences weak or no erections as this enzyme prevents the normal blood flow to the penis. By inhibiting PDE-5, Sildenafil fosters the erectile process. More blood flows to the penis due to relaxed smooth muscles. Once it happens a man has stiff and hard erection.
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Several studies of Sildenafil were conducted in patients with different ED causes, physical and psychological including patients with diabetes mellitus, nerve damage, hypertension, heart disease and atherosclerosis. In eight double-blind placebo-controlled crossover studies of the drug in patients with diagnosed impotence, the sexual arousal in men after dosing led to improved erectile function.
The improvements in erectile function were estimated with an objective measuring tool RigiScan. The erections were assessed in two main positions: the duration and the rigidity. Besides, men taking part in these studies were asked to make self-assessment after using Viagra.
Most studies observed that the medication was effective about 45-60 minutes after dose, still some patients had sexual response 15 minutes post dose.
The erectile response assessed by RigiScan was increasing with the dose enlargement as plasma concentration of the drug increased.
The duration of the drug was up to 4 hours.
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If you decide to start the treatment with generic Viagra it is always necessary to consult your doctor. If you buy your Viagra online without prescription, you should know all the information about this drug to use it safely, especially if you take it for the first time. Still if you have other serious heart conditions, liver or kidney impairment or a certain cardiovascular status, you need a doctor’s consultation before using Viagra pills.
Viagra may cause allergic reactions in very rare cases. If you think that any Viagra component will cause allergy in you, do not take it.
Never take Viagra with drugs for lowering blood pressure and nitrates. You may experience a serious side effect of both medications- a significant decrease in blood pressure.
In case you suffer from any health condition from the list below, inform your doctor before using Viagra:
· Heart rhythm abnormalities;
· A history of congestive heart failure;
· Uncontrolled hypertension and hypotension;
· Coronary artery disease;
· Stomach ulcers;
· Any bleeding disorder;
· Retinitis pigmentosa;
· Any blood cell disorder;
· Physical deformities of the penis caused by trauma or congenital deformity;
· Other conditions.
It is urgent to tell your doctor if you take other medications on a regular basis, they may interact with Viagra, increasing or decreasing its effects or the concomitant usage of Viagra and other medication may lead to serious side effects.
Viagra – Sildenafil Citrate
Viagra medication is one of the best revolutionary tools for the treatment of most unpleasant condition in men – erectile dysfunction or impotence. This medication has been improving sexual disorders since its approval for the treatment of ED in men in 1998. For many men this medication has become everyday accessory which they can fully trust.
Viagra – Sildenafil citrate is a vasodilating agent, a phosphodiesterase type 5 (PDE 5) inhibitor working by muscle relaxation and improving blood flow into the penis. It is clinically proven that men with certain health disorders causing ED benefit from using Sildenafil.
Viagra is recommended by most experts in sexual health and offered as first-line treatment for Erectile Dysfunction except when Generic Viagra is contraindicated.
Viagra is a PDE5 inhibitor indicated for erectile dysfunction in men, it is a prescription medication, but the majority of men purchase it without prescription. Viagra online has become a number one oral ED medication in the United States, Europe, New Zealand and Australia as it is highly advertised and popular among doctors and patients.
Viagra facts may be interesting for those who have an intention to buy it and those who have already used it.
Viagra is a brand name of the chemical substance Sildenafil citrate which was patented in 1996 by Pfizer.
Sildenafil was initially tested as a hypertension and angina therapy, but the researchers noted its beneficial results in test participants with impotence.
Sildenafil has become the first oral drug licensed and advised by FDA as erectile dysfunction therapy in the US in 1998.
The period of Viagra marketing 1999-2001 brought Pfizer more than $1 billion.
Doctors and sex experts are concerned by large recreational usage of Viagra by people of both genders.
According to the statistics 92% of sales of all prescribed oral medications for ED owned by brand Viagra in 2000.
The end of Pfizer’s patent for Sildenafil in the US falls on 2012.
People about ED drugs
I want to say to my provider thanks for Viagra! I’m only forty five but had been ED (erectile dysfunction) , I don’t keep or get an erection. My specialist said it was my very stressful workload. He recommended to me the 50mg Viagra and I had a good results with this drug. I buy Viagra in online shop in this site without prescription. But you should to stay away from the fake stuff. Wife and I are very active with a 3 year old and in mid-30s . Highly recommend this drug.